Product Description
Ingredients: Stearoylethanolamide. Suggested Use: Take 1 capsule, 1-3 times per day or as directed by your healthcare practitioner.
I was very excited to learn about this substance, SEA (Stearoylethanolamide), and its promising effect on mitigating neuroinflammation.
SEA is a signaling molecule made by the body from stearic acid. Stearoylethanolamide ( SEA) is an endocannabinoid neurotransmitter
Over the last 80 years, stearic acid levels of Americans have dropped from around 8% of bodyfat to around 3%. This has likely led to a decline in SEA levels relative to the other ethanolamides.
Studies in rodents have shown SEA to reduce appetite (Terrazzino, 2004), suppress the enzyme SCD-1 in the liver and to have powerful anti-inflammatory effects (Berdyshev, 2015).
Stearoylethanolamide interferes with retrograde endocannabinoid signalling and supports the blood-brain barrier integrity under acute systemic inflammation
- PMID: 31881191
- DOI: 10.1016/j.bcp.2019.113783
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